Central Research Institute or CRI was set up in Kasauli in 1905 during the time of Britishers. The place is thronged all through the year by tourists who come here to visit the beautiful campus ground. CRI is engaged in some research and development activities and has created vaccines for treating various diseases and ailments including cholera, typhoid, smallpox, and snakebite. Sir David Semple was the first director of this institute and it is under him that the organisation worked in the area of immunology and virological research.
The institute is responsible for the development of vaccines for rabies and snakebite.The institute also provides academic courses apart from medical research and development. Administered by the Ministry of Health and Family Welfare, this institute offers graduate and post-graduate courses. The CRI is internationally known for its contribution in the medical field. At present, the organisation is working in collaboration with the World Health Organisation or WHO for the preparation of vaccines for diseases such as polio, measles, and DTP.