The Palayur Church is a tourist favourite in Guruvayur. This church was laid by St. Thomas, an apostle of Jesus Christ. Out of seven churches built by the noted Apostle, this church is one of them. The beauty of this church lies in its architectural beauty which depicts the life and work of St. Thomas.
There were about fourteen granite idols in the church that portrays the life and work of the Apostle at different stages. These statues can be seen at the entrance of this church.
During the celebration of the Palayur Mahatheerthadanam festival, devotees from every nook and corner of India come here carrying a wooden cross. Muppittu Njayar, Thukharana Thirunal and Tharpana Thirunal are other important events conducted at the Palayur Church. Newborn babies are brought to this church on Muppittu Njayar for baptising.