Wayanad is well connected with other cities via national highways. There are intersections from Kozhikode, Kannur, Ooty and Mysore leading to Wayanad. However, one has to be well stocked with foods and drinks as you may not find many restaurants about 100 km from Wayanad. Also, travel with a full petrol tank and keep getting it filled in between as there aren't many petrol stations on the way to Wayanad.
Head northwest on Vittal Mallya Rd
Take the 1st left onto Kasturba Rd/Rajaram Mohan Roy Rd/Vittal Mallya Rd
Turn right onto Kasturba Rd/Rajaram Mohan Roy Rd
Take the 1st right to stay on Kasturba Rd/Rajaram Mohan Roy Rd
At Corporation/Hudson Cir, take the 1st exit onto Bangalore - Mysore Rd/Kasturba Rd
Sharp right at IBS Bangalore to stay on Bangalore - Mysore Rd
Continue onto Ashoka Rd
At Chamaraja Cir, take the 3rd exit onto Albert Victor Rd/SH 88
At the roundabout, take the 1st exit onto Sayyaji Rao Rd
At the roundabout, take the 2nd exit onto 101 Ganapathi Rd
Turn left
Take the 1st right
Turn left toward Mananthavadi Rd/SH 33
At the roundabout, take the 3rd exit onto Mananthavadi Rd/SH 33
Turn right to stay on SH 33
Turn right to stay on SH 33
Continue onto Kartikulam Tholpetty Rd
Turn left onto Koyleri - Kattikulam Rd
Turn left onto Mananthavady-Koyileri-Panamaram Rd
Continue onto Calicut Rd/Kalpetta - Mananthavadi Rd
Slight left