Rameshwaram is well connected with Chennai via road. Taxis and buses ply to Rameshwaram on a regular basis from Chennai. You can chose from luxury Volvo buses as well as state run buses to Rameshwaram. Volvo buses charge around 500 INR to Rameshwaram and the state buses charge between 100-150 INR.
Head west on Joithe Ram Linghm St toward Dasathapuram/Rutland Gate 6th St
Turn left at Chaitanya State Emporium onto Nungambakkam High Rd
At the roundabout, take the 3rd exit
Slight left onto Anna Salai
At church, continue onto Taluk Office Rd
Keep right to stay on Taluk Office Rd
Continue onto Sardar Patel Rd
Continue onto Anna Salai
Continue onto Grand Southern Trunk Rd
At Tambaram Junction, continue onto Nagapattinam-Chennai Hwy/NH 45/Tiruchi-Chennai Hwy
Slight right onto Tiruchi-Chennai Hwy/NH 132/NH 45
Slight left onto NH 67
Turn left onto Indira Gandhi St
Slight left onto Ramanathapuram Rd
Turn right to stay on Ramanathapuram Rd
Take the 2nd left to stay on Ramanathapuram Rd
At the roundabout, take the 3rd exit and stay on Ramanathapuram Rd
Continue onto NH 210/NH 226
Turn right onto NH 210/State Highway 191A
Keep left to continue on NH 210
Turn right to stay on NH 210
Turn right onto ECR
Turn left onto E Coast Rd/SH 200
Turn left onto Kochi - Dhanushkodi Rd