Mayiladuthurai is a major Railway junction in the Southern Railway network. The Southern Railway system of India has regular, frequent options between cities and towns. Trains from Bhubaneswar, Chennai, Coimbatore, Karaikal, Madurai, Mannagudi, Rameswaram, Mysore, Tiruchy, Tirupathi, Tiruchendur and Varanasi travel to Mayiladuthurai nearly every day. An advantage of taking the train over an airplane is that trains arrive in Mayiladuthurai while if travelling by air is chosen then a journey by road is inevitable.